Platelets as Immune Cells
نویسندگان
چکیده
منابع مشابه
Platelets as immune-sensing cells.
Publisher's Note: This article has a companion Point by Brass et al. Publisher's Note: Join in the discussion of these articles at Blood Advances Community Conversations.
متن کاملEmerging Evidence for Platelets as Immune and Inflammatory Effector Cells
While traditionally recognized for their roles in hemostatic pathways, emerging evidence demonstrates that platelets have previously unrecognized, dynamic roles that span the immune continuum. These newly recognized platelet functions, including the secretion of immune mediators, interactions with endothelial cells, monocytes, and neutrophils, toll-like receptor (TLR) mediated responses, and in...
متن کاملNovel Functions of Therapeutic Platelets as “Immune Cells”
Platelet components are commonly transfused to bleeding in patients in the absence of a suitable alternative. If one exempts granulocyte concentrates, this labile blood component is associated with the most common infectious and immune-related hazards. Though infection can be prevented, immune-related reactions are more difficult to combat because the physiopathology is not fully understood. Re...
متن کاملEmerging roles for platelets as immune and inflammatory cells.
Despite their small size and anucleate status, platelets have diverse roles in vascular biology. Not only are platelets the cellular mediator of thrombosis, but platelets are also immune cells that initiate and accelerate many vascular inflammatory conditions. Platelets are linked to the pathogenesis of inflammatory diseases such as atherosclerosis, malaria infection, transplant rejection, and ...
متن کاملEditorial: Platelets as Immune Cells in Physiology and Immunopathology
Blood platelets are essential for the earliest stages of coagulation, namely, primary hemostasis. They adhere to damaged vessel endothelium, stick to each other (aggregate), and form clots; this prevents bleeding. For most physicians, those attributes of platelets are exactly what they learned in medical school years ago, and this basic knowledge seems quite enough to allow a valid therapeutic ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation Research
سال: 2007
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.0000252802.25497.b7